Some people may experience joint pain that is chronically dull, while others describe it as sharp or stabbing pain
Phase 3 Update (2026): Early data from the TRIUMPH-4 trial showed even more impressive results at 68 weeks: 28.7% average weight loss on the 12mg dose (approximately 71 lbs for a 240-lb person)
These combined effects make GLP-1 medications a powerful option for improving overall health in people with these conditions
The article explains that GLP-1 agonists slow gastric emptying and reduce appetite, so overall fluid and nutrient intake can drop if hydration is not deliberately maintained
Yadav P, Ortega JG, Tamaki W, Chien C, Chang KC, Biswas N, et al
Anesthesia teams are trained to manage patients on GLP-1 drugsthey simply take extra precautions