The result is a compound that reduces appetite through GLP-1, enhances insulin sensitivity through GIP, and actively burns stored fat through glucagon receptor engagement
Remarkably, up to 40% of individuals who received the highest two doses of survodutide (BI 456906) achieved a weight loss of at least 20%
Nasr et al
Most patients experience constipation relief within 24 weeks as the body adapts, but some require ongoing dietary or pharmacological support throughout treatment
Kato T, Niizuma S, Inuzuka Y, Kawashima T, Okuda J, Tamaki Y, Iwanaga Y, Narazaki M, Matsuda T, Soga T, Kita T, Kimura T, Shioi T (2010) Analysis of metabolic remodeling in compensated left ventricular hypertrophy and heart failure
Fisiologa del GLP-1 GLP-1 es una incretina producida en el intestino en respuesta a la ingesta de alimentos