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Other Considerations Complexity is inherent to the identification of patients who might benefit the most from mecasermin treatment as access to testing required for the definitive diagnosis of SPIGFD (e.g., GH antibody testing, genetic testing, or a clear test to assess IGF-1 response to GH [an IGF-1 generation test]) is limited in many Canadian jurisdictions

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Improves Fat Metabolism The dual-agonist effect appears to have a more profound impact on how the body stores and utilizes fat, contributing to greater weight loss and improved lipid profiles

The genetic test examines key variants such as GLP1R rs6923761 and MC4R rs17782313, which influence how your body responds to GLP-1 medications and regulates appetite and energy balance