Regarding water retention specifically , GLP-1 receptor agonists do not typically cause fluid retention
Thyrotoxicosis - investigation and management
To qualify, you need to meet one of the following requirements when starting GLP-1 treatment: A BMI (body mass index) of 35 or higher A BMI between 30 and 34.99, with one or more additional conditions: Diastolic heart failure Uncontrolled high blood pressure/hypertension Chronic kidney disease, stage 3a or higher Prediabetes Previous heart attack or stroke Blocked arteries in arms or legs with symptoms A BMI between 27 and 29.99, with one or more additional conditions: Prediabetes Previous heart attack or stroke Blocked arteries in arms or legs with symptoms Medicare beneficiaries who have sleep apnea, diabetes or fatty liver disease can't access the program, but their Medicare Part D insurance might cover their GLP-1s separately based on those diagnoses
Some people only think of diabetes when they hear insulin
In addition, GLP-1RAs interfere with the ability of other addictive drugs to activate the mesolimbic dopamine system
While the body produces glutathione on its own, production can struggle to keep up during times of excess stress, immune challenges, unhealthy microbial environments, or during aging