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Systematic reviews identify 36 studies demonstrating that BPC-157 improves functional, structural, and biomechanical outcomes across muscle, tendon, ligament, and bone injuries in preclinical models, with the peptide enhancing collagen synthesis, improving tensile strength, and accelerating cellular proliferation in tendon fibroblasts through FAK-paxillin pathway activation critical for cellular adhesion, migration, proliferation, and survival

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Preclinical wound healing Animal wound-healing studies in rats, mice, rabbits, and pigs reported faster wound contraction, increased collagen, and improved angiogenesis with GHK-Cu, including systemic effects when GHK-Cu was injected at one site and improved healing at distant sites