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We acknowledge this potential bias and strive for a balanced and objective overview

Given that serum melatonin concentrations are higher in pregnant than in non-pregnant women, studies have indicated that the primary source of this melatonin is the placenta (34, 64)

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Pan-cancer data was normalized utilizing the R package DESeq2s Median of Ratios Normalization ( Immune deconvolution data was downloaded from the TIMER2.0 database under the filename Infiltration Estimation, ( Institutional review board approval This study was approved by the Northwell Health Institutional Review Board (IRB #24-0335)

Moderate ROS can reinforce PI3K/AKT/mTORC1 activation, whereas excessive accumulation induces oxidative stress and inactivates key components, shifting the balance toward cell death [48, 49]