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Lancet 378(9790):487497

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These data suggest that a reduction of ghrelin using GOAT inhibitors is not sufficient to induce clinically relevant body weight loss

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statistically significant improvement in motor symptoms Another trial with once-daily self-administered injections of liraglutide (1.2 or 1.8 mg, as tolerated) or placebo in 62 patients with PD reported improvements in MDS-UPDRS-2 (an activity of daily living scale), but not in MDS-UPDRS-3, in treated patients vs placebo