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Disrupted iron homeostasis in the brain has been increasingly implicated in the pathology of many CNS diseases, where excessive iron accumulation can lead to oxidative stress, neuroinflammation, and ferroptotic cell death in vulnerable brain regions (Salvador et al., 2010)

d , Top ranked (z-scores) co-evolved genes with SLC25A40 across species

doi:10.3109/10837450.2014.979944 Preparation and storage Research-only handling information

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