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2.3.3 Pathway inhibitors or activators In addition to iron and TLR agonist-based nanoparticles, some pathway inhibitors or activators can also target TAMs and polarize M2-type TAMs to M1-type TAMs, such as PI3K inhibitors, c-MYC inhibitors, NF-B and IRF5 activators

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Current findings are derived from experimental and preclinical research models, and outcomes vary based on study design and biological context

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