compound tirzepatide vs compounded semaglutide Episode 19: Doctor Panel -

the right choice depends on your health needs and goals

According to the platform's terms of use, TomorrowsRx itself is not a healthcare provider

Robert Kushner: Well, the BMI classifications, the cut points you mentioned, have actually now been removed by the FDA for semaglutide and the other drug called tirzepatide, the two major drugs on the market

A 2025 meta-analysis in PMC (covering 36,754 tirzepatide and 106,057 semaglutide participants across multiple studies) confirmed tirzepatides advantage, finding an average 4.23 percentage points greater weight loss with tirzepatide an effect that was both dose- and duration-dependent

The trade-off is pace

The standard titration schedule for Ozempic begins at 0.25 mg once weekly for four weeks, increasing to 0.5 mg weekly, with further escalation to 1 mg or 2 mg if additional glycaemic control is required