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The scientific details are covered comprehensively in the published clinical trial literature see the Selected Research References at the end of this article

[DOI] [PubMed] [Google Scholar] 20.Santus P, Signorello JC, Danzo F, Lazzaroni G, Saad M, Radovanovic D

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Test solution: Transfer an appropriate amount of the substance, accurately weighed, to a suitable container

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This is one reason the 5mg/ml concentration exists, because it keeps even the highest maintenance doses well within the capacity of a standard syringe