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doi:10.1111/j.1440-0960.2011.00745.x 2Yip L, Zaloumis S, Irwin D,

In placebo-controlled adjunctive epilepsy trials in adults receiving topiramate 200 to 1,000 mg/day, hot flashes (1% to 2%), drug-induced body odor (0% to 1%), skin disorder (1% to 2%), hyperhidrosis (1% or less), and erythematous rash (1% or less) were reported with equal or greater frequency than placebo

I'm walking around thinking, 'Is this how other people feel normally?'" says Sipes

The logical extension was: what if we could design or replicate peptides to achieve specific outcomes

Available online at: (Accessed April 1, 2025)

Spreading protein intake evenly throughout the day (rather than loading it all into one meal) can also improve muscle protein synthesis