Nevertheless, despite some recent progress and the demonstration of its key role in the inhibition of hepatic gluconeogenesis, the exact nature of the mitochondrial interaction between the drug and the complex 1 is still poorly characterized
See full safety information below
doi: 10.1186/s12944-016-0289-1 142 LuHSuSAjuwonKM
Drugs such as GLP-1 receptor agonistsincluding semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro)are now household names, praised for their ability to reduce appetite, regulate blood sugar, and promote sustained weight loss
[DOI] [PMC free article] [PubMed] [Google Scholar] 209.Sandoval DA, Bagnol D, Woods SC, DAlessio DA, Seeley RJ
We have no actual safety data, those studies havent been done and wont be done due to ethical issues