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GSSG is a product of the oxidation of GSH, which has no biological activity and needs to be reduced to GSH by consuming energy under the action of enzymes in order to resume its function

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J Neurochem 114:820831 Shinohara M, Saitoh M, Takanashi J, Yamanouchi H, Kubota M, Goto T, Kikuchi M, Shiihara T, Yamanaka G, Mizuguchi M (2011) Carnitine palmitoyl transferase II polymorphism is associated with multiple syndromes of acute encephalopathy with various infectious diseases