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Inflammatory and oxidative stress responses of healthy adults to changes in personal air pollutant exposure

5-Amino-1MQ produces fat reduction through pure expenditure and lipogenesis suppression

Sci Immunol (2017) 2(10):eaam6346

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Meanwhile, BOLA3 deficiency can downregulate glycine cleavage system protein H (GCSH), leading to intracellular glycine accumulation, inducing a metabolic shift towards glycolysis and fatty acid oxidation, generating reactive oxygen species, promoting endothelial cell proliferation, survival, and vasoconstriction, and reducing angiogenic capacity (Yu et al., 2019)