The results were striking: participants receiving the highest 12 mg dose achieved mean weight loss of approximately 24.2% of baseline body weight at week 48, compared to just 2.1% with placebo - representing an astounding 22 percentage point placebo-adjusted treatment effect
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Dry eye syndrome is caused by decreased tear production caused by age, medical conditions (diabetes, rheumatoid arthritis, thyroid disorders), or medications (antihistamines, decongestants, blood pressure medications)
CBO notes that some analyses of weight loss via GLP-1s found they reduced all-cause mortality in certain patients, while other methods had mixed results notably bariatric surgery, which did not clearly lower future health spending and was heavily dependent on individual adherence to post-surgery lifestyle changes
Coordinating with endocrinology to address the full spectrum of PCOS symptoms while using GLP-1 therapy produces better outcomes than treating weight in isolation
