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During one experiment using a murine model, Pal-GHK was suggested to suppress the activation of Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-B) and p38 mitogen-activated protein kinase (MAPK) signaling pathways, both of which are associated with inflammation

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Meanwhile, the phosphorylation level of p38 MAPK was significantly elevated, and its ferroptosis inhibitors, SB202190, reduced ROS production, restored the expression of ferroptosis - related genes, and promoted cell survival by blocking this pathway