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Yes, GLP-1-based therapies are FDA-recommended for weight loss, particularly in individuals with a BMI over 30 or those who did not have success with other weight-loss methods

Additionally, further investigations proved that a blockade of GLP-1R could result in the GFR reduction and NHE3-mediated sodium reabsorption enhancement in the proximal tubule (100)

JAMA 2021;325:1403-13.ArticlePubMed 32

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