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GST M2-2 is a prostaglandin E synthase in the brain cortex [8] and rat GST A1-1 and GST A3-3 catalyze the reduction of PGH 2 to PGF 2

If fatigue emerges, increase calories by 100200 per day until energy stabilizes while continuing to lose weight

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Candeias et al., 2015)

Animal model metabolomics studies reveal that HFD-induced NAFLD is characterized by hepatic saturated fatty acid (myristic acid, palmitic acid) and monounsaturated fatty acid (oleic acid) accumulation, accompanied by decreased gluconeogenic amino acid (glycine, alanine, aspartic acid, glutamic acid, proline) levels (95)

189 TRIM24-mediated regulation of glioma stem cell proliferation and selfrenewal has also been reported