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These biomarkers don't predict exact outcomes but can support informed provider discussions

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The broader GLP-1 class also remains under active legal scrutiny: more than 4,400 lawsuits have been filed against Eli Lilly and Novo Nordisk in multidistrict litigation alleging failure to warn about gastroparesis and vision loss linked to existing semaglutide and tirzepatide products, though neither orforglipron nor retatrutide is named in that litigation