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Similar content being viewed by others Facts Nrf2 plays a pivotal role in the regulation of essential genes involved in ferroptosis and is intimately linked to the progression of lung diseases

Since mitochondria are essential to our very existence, it is unsurprising that the effects of mitochondrial diseases can be severe, and sometimes lethal, spanning a wide-ranging spectrum of physiological and biochemical symptoms [1,3,4] (see Table 1 for examples)