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Indeed, at the end of the study, the decrease in SMI exceeded 40% of total weight loss in only 18% of patients and, most importantly, the HG and MQI (both indicative of muscular functional status) were not significantly different at each time compared to baseline (see Table 4)

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doi: 10.4161/psb.24138 70 ShiJ.FuX.-Z.PengT.HuangX.-S.FanQ.-J.LiuJ.-H

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Biosimilars must demonstrate comparable efficacy and safety to originator drugs through rigorous comparative clinical trials

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