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In vitro studies demonstrated that supplementation of Gly protects intestinal epithelial cells against inflammatory oxidative stress (118), and reduces pro-inflammatory cytokine production while enhancing IL-10 expression of LPS-stimulated monocytes (119)

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GLP-1 combination therapies or follow-ons may also arrive

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The good news is that GLP-1 fatigue is usually temporary and can often be prevented or improved with the right support