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Gebauer, F., Schwarzl, T., Valcarcel, J

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What clinical trials measure Clinical trials for weight loss medications track several outcomes: Percentage of body weight lost from baseline Proportion of participants achieving specific weight loss thresholds (10%, 15%, 20%, 25%+) Changes in metabolic markers (HbA1c, lipids, blood pressure) Safety and tolerability (adverse events, discontinuation rates) How much weight loss has retatrutide shown

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In contrast, the drug approved for weight-loss Wegovy was mostly used on-label: 81% of patients prescribed Wegovy had overweight or obesity diagnoses