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Collagen-based cell migration models in vitro and in vivo

Injectable B12 delivers the vitamin directly into the bloodstream, allowing for immediate absorption

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It stimulates collagen I and III production, increases elastin by 30%, raises decorin levels (which organizes collagen structure), and modulates matrix metalloproteinases to remodel damaged or disorganized collagen

Given that there is no placebo-controlled human data, no established dose, and a mechanism whose foundational papers were retracted, an absence of noticeable effect is fully consistent with the current evidence it does not necessarily indicate a defective product, the wrong route, or an insufficient duration

Oral bioavailability of dihexa is negligible