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The integration of a polyphenol-vanadium system with the EZH2 degrader YM281 proteasome-targeting chimeric (PROTAC), encapsulated in methoxy polyethylene glycol-NH2 to form a novel multifunctional nano PROTAC (YM@VBM), can activate antitumor immunity by reducing MDSCs and inhibit tumor growth (135)

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Mullur N, Morissette A, Morrow NM, Mulvihill EE

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