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Semaglutide, marketed under the brand names Ozempic, Wegovy, and Rybelsus, is a GLP-1 agonist available in various forms, including weekly injections (Ozempic for diabetes and Wegovy for obesity) and daily oral tablets (Rybelsus)

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Therefore, an increased supply of Met may increase antioxidant production, potentially aiding in the relief of oxidative stress and inflammation triggered by the production of reactive oxygen metabolites ( Conversely, Hcy has the capacity for remethylation to regenerate methionine, which relies on the folate cycle and vitamin B 12 ( Figure 1 ) ( 2 -THF), which is subsequently reduced to 5-methyltetrahydrofolate (5-CH 3 -THF) (Preynat et al., 2009)

cohort assignment was fixed by the index agent and not redefined thereafter