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People who take the medication generally lose between 15% and 25% of their body weight in a year, studies found

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The study measured weight loss at 24 weeks and 48 weeks

The dose escalation schedule also influences the timeline

DRD2 activation triggers -arrestin2 to bind with and dimerize PKM2 DRD2 activation stimulates both the classical G protein pathway and -arrestin-biased signaling, resulting in distinct downstream events 41,42,43