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Microarray analyses have revealed that GHK-Cu can modulate the expression of over 4,000 genes in human fibroblast cultures, with notable upregulation of genes associated with the ubiquitin-proteasome system, DNA repair mechanisms, and antioxidant defense pathways

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and FasL), can induce apoptosis of tumor cells, triggering ICD that promotes DCs maturation thereby activating CD4 + /CD8 + T cells to eradicate primary tumors and inhibit distal tumors (225)

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