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While the emphysema state results in loss of alveolar spaces and low sputum production, the bronchitis phenotype results in narrowing of the airways as well as blocking of the alveolar spaces with mucus obstruction leading to chronic cough, sputum production, and exacerbations (Szalontai et al., 2021

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[29] Alle negen onderzoeken werden gebruikt om de veiligheid te beoordelen en vijf van deze onderzoeken werden gebruikt om de werkzaamheid van tirzepatide te beoordelen