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These symptoms should be monitored and reported to your trial clinician if they are persistent or severe

Preclinical data indicated that tirzepatide exhibited an affinity for GIPR equivalent to GIP binding, while its affinity for GLP-1R was approximately five times weaker compared to GLP-1 (63)

However, it also means patients pay monopoly prices for years before generic competition can drive costs down

Overgaard RV, Navarria A, Hertz CL, Ingwersen SH

In research, this double action distinguishes it from uni-action medications, enabling it to be more adaptable for individuals with both diabetes and obesity

Am J Clin Nutr 8:540546