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Patients seeking GLP-1 therapy outside approved indications would generally need to pursue private prescription, which carries significant costs that may vary considerably

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other abbreviations as in Table 1

Thats why statins, PCSK9 inhibitors, and ezetimibedrugs that lower LDLare cornerstones of heart disease prevention

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This dual mechanism is why tirzepatide is widely considered a breakthrough in the GLP-1 drug class