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91 , e01603e01617 (2017)

The medication is administered as a once-weekly subcutaneous injection, with 2.5 mg used as an initiation dose for tolerability

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In adults these medications alter glucose metabolism, appetite signaling, and gastrointestinal motility

This approval underscores its efficacy in promoting significant weight loss when combined with lifestyle modifications like a reduced-calorie diet and regular physical activity

These include muscle weakness (difficulty climbing stairs, rising from a chair, or lifting objects), persistent muscle pain or tenderness, visible muscle swelling or changes in muscle appearance, or dark-colored urine, which may indicate rhabdomyolysisa rare but serious condition involving muscle breakdown