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319 Additionally, in aging osteoprogenitor cells, telomere attrition, DNA damage, and dysregulation of signaling pathways such as mTORC1 and Nrf2 reduce bone formation

The water-soluble nature of B12 means toxicity is virtually unknown, as excess is readily excreted renally

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doi:10.1038/s41586-024-07419-8 [4] Knudsen LB, Lau J

A committee vote concerning named bulk substances cannot be generalized to every product sold under the same familiar peptide name