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doi:10.1145/3546068

December 5 Product: AstraZenecas Imfinzi Indication: Limited-stage small cell lung cancer AstraZeneca on Wednesday successfully expanded the label of its PD-L1 blocker Imfinzi (durvalumab), notching the FDAs greenlight for its use in patients with limited-stage small cell lung cancer who have not progressed after concurrent platinum chemotherapy and radiation therapy

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HGF, the ligand of c-MET, is secreted as a single chain 83 kDa precursor protein containing an N-terminal (N) domain, four consecutive kringle (K1K4) domains, and a serine protease homology (SPH) domain (Fig

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