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Additionally, colorectal cancer LN metastases develop through a wide evolutionary bottleneck, resulting in polyclonal and polyphyletic phenotypes

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[DOI] [PubMed] [Google Scholar] 156.Xu X, Lin L, Chen P, Yu Y, Chen S, Chen X, et al

While TNF- was also reported as modified in blood, results were inconsistent, reporting increases [13, 29], decreases [12, 30] or no change [32, 39, 44, 60, 67], both within small or large cohorts

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