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Head-to-head data show HbA1c reductions of 2.02.3 percentage points versus 1.61.9 points for single-receptor comparators [2]Eli Lilly, SURPASS Program Results, lilly.com

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Weight loss tends to reverse when the drugs are stopped, and little is known about maintenance strategies, such as lower doses or less frequent dosing

Per one study, doses of about 50100 mg/kg/day are generally well tolerated

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