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In addition, when circulating L-carnitine concentration increases, as in the case of oral supplementation, renal reabsorption of L-carnitine may become saturated, resulting in increased urinary excretion of L-carnitine (5)

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doi: 10.1038/s41423-025-01278-7 91 HidalgoALibbyPSoehnleinOAramburuIVPapayannopoulosVSilvestre-RoigC

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The elevated intracellular lactate and reduced pyruvate concentrations align with a metabolic shift towards anaerobic glycolysis, even under normoxic conditions