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Science 362, eaau5324

Some people may experience mild nausea, stomach discomfort, or a fishy body odour at very high doses (4000mg+)

Studies also provide evidence for fast suppression of basophil responses, modulation of T-cell and B-cell subsets, induction of FoxP3-positive regulatory T-cells, and production of IgG4 blocking antibodies that compete with IgE for allergen binding

IV folic acid for severe folate deficiency