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On raw weight-loss numbers, retatrutide reached a numerically larger mean reduction (about 24% at 48 weeks in phase 2) than tirzepatide (about 22.5% at 72 weeks in phase 3), and its sponsor-reported phase 3 topline figures are higher still

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The formulation acts at multiple regulatory nodes along the gut-pancreas-peripheral tissue axis, simultaneously boosting hormone secretion and improving cellular glucose utilization

If those trials go well, and the medication is approved, it may become available on the NHS as a treatment option

If you're evaluating GLPatch because you want to avoid injections, the conversation now has more options in it than it used to

Current FDA-approved treatments for alcohol use disorder include disulfiram, acamprosate, and naltrexone