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doi: 10.1016/s0304-3835(01)00797-2 72 XinHDengYCaoJ

GLP-1R signaling in microglia helps reverse the polarization of these immune cells from a pro-inflammatory state to an anti-inflammatory state, thus reducing neuroinflammation

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Comparison with Protein Biologics Relative to larger protein drugs, peptides often offer advantages in manufacturing, stability, and delivery

However, starting at a full dose too often causes side effects like bloating, nausea, or constipation