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Suppression of placental metallothionein 1 and zinc transporter 1 mRNA expressions contributes to fetal heart malformations caused by maternal zinc deficiency

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doi: 10.1038/s41581-023-00683-3 5

The peptide delivers controlled minimal copper amounts, prevents copper-mediated oxidative damage, has 40+ years of safe use history, and requires doses thousands of times higher than therapeutic range to cause toxicity

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Hydroxocobalamin can be further converted into the active forms, adenosylcobalamin and methylcobalamin for cellular uptake