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They also play various roles in immune function and nervous system health

Moreover, Pyy knockout mice exhibit hyperinsulinemia in both fasted and fed states compared with wild-type mice 22

Two of them are particularly dysregulated and may play a biological role in the disease, let7b and miR-503, but their DNA methylation regulation remains to be confirmed

Despite significant progress in understanding ferroptosis in AS and depression, its role in comorbid conditions remains unclear

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