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Description

Nat Med (2013) 19(10):125263

PlexusDx uses precision dosing strategies and genetic insights to match your treatment to your metabolic profile

Published 2022 Dec 8

Stromal cells such as cancer-associated fibroblasts (CAFs) and endothelial cells secrete a range of factorsTGF-, HGF, and soluble Jagged-1that induce EMT and activate Notch signaling, respectively, thereby increasing CSC survival, invasion, and retention in specialized niches