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The current protocol (CLI 00125 version 8.0) incorporates revisions to improve comprehension and a reduction in the total number of transfused subjects from 600 to 292 subjects following a blinded interim analysis that confirmed the overall incidence of the primary endpoint and the power of the study

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Clinical considerations and risk profile Although GLP-1 therapies are highly effective, they are not without risks

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doi: 10.1210/en.2009-0803 114 NavarroVMFernndez-FernndezRCastellanoJMRoaJMayenABarreiroMLet al