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The pivotal role of central dysfunctional, insulin-resistant adipose tissue to the evolution of advanced fibrosis in patients with T2D and NAFLD, beyond body mass index (BMI) or steatosis, has been well established [5]

In rodents, acute toxicity studies indicate that curcumin dosages exceeding 2000 mg/kg may modify liver enzymes, implying possible hepatic stress (Sirasanagandla et al., 2022)

Glutathione homeostasis and redox regulation by sulfhydryl groups

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