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( A ) Systolic blood pressure, ( B ) diastolic blood pressure, and ( C ) mean arterial pressure (MAP) in control Glp1r VSM+/+ and Glp1r VSM/ normotensive mice ( n = 1014)

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Amiodarone by contrast, gave more variable results, with the C max exceeding the transcriptomics PoDs at all timepoints (minimum BER of 0.004) but higher PoDs from the other readouts with BERs between 0.5 and 3.5 depending on timepoint and laboratory

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