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This is consistent with previous findings that fibrosis may accelerate -cell destruction or induce the destruction of -cell connectivity, leading to decreased insulin secretion [23, 32]

The role of GLP-1 signaling in hypoglycemia due to hyperinsulinism

Synaptogenesis (new connections): By stimulating HGF/c-Met activity, Dihexa promotes synaptogenesis, the formation of new synapses between neurons

PMID: 69 Greville-HeygateSLMaishmanTTapperWJCutressRICopsonEDunningAMet al

Competitive radioligand binding studies reveal nanomolar-range affinities, with the compound effectively displacing radiolabelled VEGF-A in receptor saturation experiments

PMID: 34442354