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Preclinical data indicate that acute opioid exposure stimulates MOR in the locus coeruleus (LC), suppresses norepinephrine release, and reduces adrenergic function [12]

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Metformin: Studies show that taking metformin can lead to a 5 to 7% weight loss over several months to a year

Age and Health Status: Senior pets or those with existing health conditions may require adjusted dosages

Serious side effects Serious side effects with Contrave and Wegovy are rare

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