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Without sufficient B12, your body begins to form abnormally large blood cells that cannot perform, leading to fatigue, weakness, and other malaise

Furthermore, reactive astrocytes secret neurotrophic factors such as Nrf2, which can be leveraged to promote neuroprotection and preserve cognitive function 85,96

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Arbabi L, Li Q, Henry BA, Clarke IJ (2021) Glucagon-like peptide-1 control of GnRH secretion in female sheep

This conversion requires the enzyme glutamatecysteine ligase (GCL, glutamate-cysteine synthase)

If 8 mg produces consistent weight loss with good tolerability, it is an excellent maintenance dose